ປະ​ເພດ​ຄຳ​ຮ້ອງ
Patent - Foreign
ປະ​ເພດ​ຄຳ​ຮ້ອງຍ່ອຍ
Patent - PCT National Phase
(10) ເລກທີ ແລະ ວັນທີການຈົດທະບຽນ
ສະຖານະ
Filed
(180) ມື້​ໝົດ​ອາຍຸ
(20) ​ເລກທີ ​ແລະ ມື້ ຍື່ນ​ຄຳ​ຮ້ອງ
LA P/749 2019.06.20
(40) ​ເລກທີ ​ແລະ ວັນ​ທີ​ເຜີຍ​ແຜ່
(86) ເລກທີ ແລະ ວັນທີ ເອກະສານ PCT
(87) and Date ເລກທີ ແລະ ວັນທີ່ ເຜີຍແຜ່ PCT
(85) ວັນ​ທີເອກະສານ​ເຂົ້າ
2020.12.18
(30) ລາຍລະອຽດບຸລິມະສິດ
US 62/688,611
2018.06.22
(72) ຜູ້​ປະດິດສ້າງ
(LA) DEMOPULOS, Gregory A. (United States) : 4845 Forest Avenue Se, Mercer Island, WA 98040 (US).
(LA) DUDLER, Thomas (United States) : 13410 Ne 36th Street, Bellevue, WA 98005 US
(LA) NILSSON, Bo (Swedish) : Norrtorpsviigen 39, 75655 Uppsala (SE).
(74) ຊຶ່ບໍລິສັດຕົວແທນ
(LA) Lao Trademark Agency (LAO IP AGENCY) : LLC Bldg, Nongbone Road, Ban Nongbong,Saysettha District, P.O.Box 925, Vientiane, LAO P.D.R. Tel: +(856 21) 264866, 264 877; Fax: +(856 21) 264344 E-mail: laotrmar@laotel.com; ksayavon@laotel.com Website: www.laoip.org
(54) ຫົວຂໍ້
(LA) Compositions And Methods Of Inhibiting MASP-2 For The Treatment Of Various Thrombotic Diseases And Disorders
(57) ບົດສັງເຂບ
(LA)

In one aspect, the invention provides compositionsand methods for preventing,
reducing, and/or treating a disease, disorder or condition associated
with fibrin-induced activation of the complement system and the associated activation ofthecoagulation
and/or contact systems comprising administering a therapeutic amount of a MASP-2 inhibitory antibody to a subject in need thereof. In some embodiments, the methods of the invention provide anticoagulation and/or antithrombosis and/or antithrombogenesis without affecting hemostasis. In one embodimenl of this aspect ofthe invention, the compositions and methods are useful for treating a subject is suffering from, or at risk of developing, a disease, disorder or condition associated with complement-related inflammation, excessive coagulation or contact system activation initiated by fibrin or activated platelets.

(58) ການ​ຮຽກຮ້ອງ
ປະເພດຂອງເອກະສານ ວັນທີ ການດໍາເນີນການ
ຊື່ຂອງລາຍການວັນ​ທີສະຖານະ
Filing2019.06.20Filed
PCT National Phase Entry2020.12.18PCT National Phase
Filing2021.01.25Filed